Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(5-(4-(3-butyl-4-fluorophenyl)-5-fluorothiazol-2-ylcarbamoyl)-3-chloropyridin-2-yl)piperidine-4-carboxylic acid
    Show/Hide
 PubChem ID
CID: 49798117
Canonical SMILES
CCCCc1cc(ccc1F)-c1nc(NC(=O)c2cnc(N3CCC(CC3)C(O)=O)c(Cl)c2)sc1F
    Show/Hide
Compound Formula C25H25ClF2N4O3S
Compound Structure
Protein Name
 Protein Info 
Thrombopoietin receptor
Protein Classification
Membrane receptor
Uniprot ID
P40238
Gene Name
MPL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 220 nM
   TI
   LI
   LO
   TS