Brief Information of the Compound and Protein
Compound Name
1-(3-chloro-5-(1-(2-fluoro-3-(trifluoromethyl)phenyl)-1H-pyrazol-3-ylcarbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid
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PubChem ID
CID: 49798046
Canonical SMILES
OC(=O)C1CCN(CC1)c1ncc(cc1Cl)C(=O)Nc1ccn(n1)-c1cccc(c1F)C(F)(F)F
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Compound Formula C22H18ClF4N5O3
Compound Structure
Protein Name
Thrombopoietin receptor
Protein Classification
Membrane receptor
Uniprot ID
P40238
Gene Name
MPL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
EC50 > 811 nM
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