Brief Information of the Compound and Protein
Compound Name
1-(3-chloro-5-(5-ethyl-4-(4-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-ylcarbamoyl)pyridin-2-yl)piperidine-4-carboxylic acid
    Show/Hide
PubChem ID
CID: 49798019
Canonical SMILES
CCc1sc(NC(=O)c2cnc(N3CCC(CC3)C(O)=O)c(Cl)c2)nc1-c1ccc(F)c(c1)C(F)(F)F
    Show/Hide
Compound Formula C24H21ClF4N4O3S
Compound Structure
Protein Name
Thrombopoietin receptor
Protein Classification
Membrane receptor
Uniprot ID
P40238
Gene Name
MPL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3 Mus musculus (Mouse)  1
1
EC50 = 160 nM
   TI
   LI
   LO
   TS