Brief Information of the Compound and Protein
Compound Name
 Compound Info 
N-[1-(1-adamantyl)ethyl]-10-(benzenesulfonyl)-5-thia-1,8,11,12-tetrazatricyclo[7.3.0.02,6]dodeca-2(6),3,7,9,11-pentaen-7-amine
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 PubChem ID
CID: 49799703
Canonical SMILES
CC(Nc1nc2c(nnn2c2ccsc12)S(=O)(=O)c1ccccc1)C12CC3CC(CC(C3)C1)C2
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Compound Formula C25H27N5O2S2
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 221 nM
   TI
   LI
   LO
   TS
2
Ki = 103 nM
   TI
   LI
   LO
   TS