Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyrazolo[1,5-a]pyridine
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 PubChem ID
CID: 10336538
SID: 15347559
Canonical SMILES
Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1
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Compound Formula C18H19ClN4
Compound Structure
Protein Name
 Protein Info 
D(4) dopamine receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
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Dopamine receptor
Uniprot ID
P21917
Gene Name
DRD4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
Ki = 2.188 nM
   TI
   LI
   LO
   TS
2
Ki = 2.2 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 6.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 154 nM
2 Ki = 2.2 nM
3 Ki = 2.7 nM
4 Ki = 3.1 nM