Brief Information of the Compound and Protein
Compound Name
3-{5-chloro-4-[2-methyl-4-(2-methyl-2H-pyrazol-3-yl)-quinolin-8-yloxymethyl]-pyridin-3-yl}-N,N-dimethyl-propionamide
    Show/Hide
PubChem ID
CID: 44190756
SID: 85186445
Canonical SMILES
CN(C)C(=O)CCc1cncc(Cl)c1COc1cccc2c(cc(C)nc12)-c1ccnn1C
    Show/Hide
Compound Formula C25H26ClN5O2
Compound Structure
Protein Name
B2 bradykinin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Bradykinin receptor
Uniprot ID
P30411
Gene Name
BDKRB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 36 nM
   TI
   LI
   LO
   TS
CL000837 HF1-5 Rattus norvegicus (Rat)  1
1
IC50 = 73 nM
   TI
   LI
   LO
   TS