Brief Information of the Compound and Protein
Compound Name
4-(8-((3,5-dichloropyridin-4-yl)methoxy)-2-methylquinolin-4-yl)-3-methylisothiazole
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PubChem ID
CID: 44190168
SID: 85185828
Canonical SMILES
Cc1nscc1-c1cc(C)nc2c(OCc3c(Cl)cncc3Cl)cccc12
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Compound Formula C20H15Cl2N3OS
Compound Structure
Protein Name
B2 bradykinin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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Bradykinin receptor
Uniprot ID
P30411
Gene Name
BDKRB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 200 nM
   TI
   LI
   LO
   TS
CL000837 HF1-5 Rattus norvegicus (Rat)  1
1
IC50 = 330 nM
   TI
   LI
   LO
   TS