Brief Information of the Compound and Protein
Compound Name
N-[[5-chloro-4-[[2-methyl-4-(2-methylpyrazol-3-yl)quinolin-8-yl]oxymethyl]pyridin-3-yl]methyl]methanesulfonamide
    Show/Hide
PubChem ID
CID: 44190941
SID: 85186631
Canonical SMILES
Cc1cc(-c2ccnn2C)c2cccc(OCc3c(Cl)cncc3CNS(C)(=O)=O)c2n1
    Show/Hide
Compound Formula C22H22ClN5O3S
Compound Structure
Protein Name
B2 bradykinin receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Short peptide receptor (family A GPCR)
>
Bradykinin receptor
Uniprot ID
P30411
Gene Name
BDKRB2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000006 HEK293 Homo sapiens (Human)  1
1
IC50 = 14 nM
   TI
   LI
   LO
   TS
CL000837 HF1-5 Rattus norvegicus (Rat)  1
1
IC50 = 110 nM
   TI
   LI
   LO
   TS