Brief Information of the Compound and Protein
Compound Name
Azimilide
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PubChem ID
CID: 9571004
SID: 14833668
Canonical SMILES
CN1CCN(CCCCN2C(=O)CN(/N=C/c3ccc(-c4ccc(Cl)cc4)o3)C2=O)CC1
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Compound Formula C23H28ClN5O3
Compound Structure
Protein Name
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
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Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 560 nM
   TI
   LI
   LO
   TS
2
IC50 = 1412.54 nM
   TI
   LI
   LO
   TS
CL000083 MCF-7 Homo sapiens (Human)  1
1
IC50 = 562.34 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 400 nM
2 IC50 = 562.34 nM
3 IC50 = 1412.54 nM