Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(4-{1-[2-(6-Methyl-pyridin-2-yl)-ethyl]-piperidine-4-carbonyl}-phenyl)-methanesulfonamide
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 PubChem ID
CID: 3185
SID: 14805888
Canonical SMILES
Cc1cccc(CCN2CCC(CC2)C(=O)c2ccc(NS(C)(=O)=O)cc2)n1
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Compound Formula C21H27N3O3S
Compound Structure
Protein Name
 Protein Info 
Potassium voltage-gated channel subfamily H member 2
Protein Classification
Ion channel
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Voltage-gated ion channel
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Potassium channels
>
Voltage-gated potassium channel
Uniprot ID
Q12809
Gene Name
KCNH2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 19.95 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  2
1
IC50 = 7.7 nM
   TI
   LI
   LO
   TS
2
IC50 = 22.91 nM
   TI
   LI
   LO
   TS
CL000083 MCF-7
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 7.762 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 25 nM
2 IC50 = 1.2 nM
3 IC50 = 7.82 nM
4 IC50 = 12.02 nM
5 IC50 = 19.95 nM
6 IC50 = 20 nM
7 IC50 = 21 nM
8 IC50 = 24.2 nM