Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-((5S,9R)-7-(5-(1H-Tetrazol-5-yl)pyridin-2-yl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-9-yl)-benzonitrile
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 PubChem ID
CID: 46224088
SID: 96078864
Canonical SMILES
CN1C(=O)N(C(=O)[C@]11CN(C[C@H]1c1ccc(cc1)C#N)c1ccc(cn1)-c1nnn[nH]1)c1cc(Cl)cc(Cl)c1
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Compound Formula C26H19Cl2N9O2
Compound Structure
Protein Name
 Protein Info 
Integrin alpha-L
Protein Classification
Membrane receptor
Uniprot ID
P20701
Gene Name
ITGAL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1.8 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 80 nM