Brief Information of the Compound and Protein
Compound Name
2-((5S,9R)-9-(4-Cyanophenyl)-3-(3,5-dichlorophenyl)-1-methyl-2,4-dioxo-1,3,7-triazaspiro[4.4]nonan-7-yl)benzo[d]thiazole-6-carboxylic Acid
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PubChem ID
CID: 46221417
SID: 96076026
Canonical SMILES
CN1C(=O)N(C(=O)[C@]11CN(C[C@H]1c1ccc(cc1)C#N)c1nc2ccc(cc2s1)C(O)=O)c1cc(Cl)cc(Cl)c1
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Compound Formula C28H19Cl2N5O4S
Compound Structure
Protein Name
Integrin alpha-L
Protein Classification
Membrane receptor
Uniprot ID
P20701
Gene Name
ITGAL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C Homo sapiens (Human)  1
1
IC50 = 4.4 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 280 nM