Brief Information of the Compound and Protein
Compound Name
 Compound Info 
5-[(5S,9R)-9-(4-CYANOPHENYL)-3-(3,5-DICHLOROPHENYL)-1-METHYL-2,4-DIOXO-1,3,7-TRIAZASPIRO [4.4]NON-7-YL]METHYL]-3-THIOPHENECARBOXYLICACID
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 PubChem ID
CID: 11635371
SID: 17493756
Canonical SMILES
CN1C(=O)N(C(=O)[C@]11CN(Cc2cc(cs2)C(O)=O)C[C@H]1c1ccc(cc1)C#N)c1cc(Cl)cc(Cl)c1
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Compound Formula C26H20Cl2N4O4S
Compound Structure
Protein Name
 Protein Info 
Integrin alpha-L
Protein Classification
Membrane receptor
Uniprot ID
P20701
Gene Name
ITGAL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000749 HUVEC-C
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 18 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 276 nM
2 IC50 = 280 nM