Brief Information of the Compound and Protein
Compound Name
4-[[(4-tert-butylcyclohexyl)-[1-methyl-5-(trifluoromethyl)benzimidazol-2-yl]amino]methyl]-N-(2H-tetrazol-5-yl)benzamide
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PubChem ID
SID: 16701895
Canonical SMILES
Cn1c(nc2cc(ccc12)C(F)(F)F)N(Cc1ccc(cc1)C(=O)Nc1nnn[nH]1)[C@H]1CC[C@@H](CC1)C(C)(C)C
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Compound Formula C28H33F3N8O
Compound Structure
Protein Name
Glucagon receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
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Glucagon-like receptor
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Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 11 nM
   TI
   LI
   LO
   TS
2
IC50 = 62 nM
   TI
   LI
   LO
   TS