Brief Information of the Compound and Protein
Compound Name
4-(4-Methylpiperazin-1-yl)-2-(1-naphthylmethyl)-1H-benzimidazole
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PubChem ID
CID: 45488165
SID: 96032696
Canonical SMILES
CN1CCN(CC1)c1cccc2[nH]c(Cc3cccc4ccccc34)nc12
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Compound Formula C23H24N4
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
Ki = 27 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 36.22 nM
   TI
   LI
   LO
   TS