Brief Information of the Compound and Protein
Compound Name
[4-(4-methylpiperazin-1-yl)-1H-benzimidazol-2-yl]-naphthalen-1-ylmethanone
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PubChem ID
CID: 45488152
SID: 96032476
Canonical SMILES
CN1CCN(CC1)c1cccc2[nH]c(nc12)C(=O)c1cccc2ccccc12
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Compound Formula C23H22N4O
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
Q9R1C8
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  2
1
Ki = 5 nM
   TI
   LI
   LO
   TS
2
Ki = 34 nM
   TI
   LI
   LO
   TS