Brief Information of the Compound and Protein
Compound Name
 Compound Info 
SB-258585
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 PubChem ID
CID: 3248571
SID: 14835051
Canonical SMILES
COc1ccc(NS(=O)(=O)c2ccc(I)cc2)cc1N1CCN(C)CC1
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Compound Formula C18H22IN3O3S
Compound Structure
Protein Name
 Protein Info 
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
>
Monoamine receptor
>
Serotonin receptor
Uniprot ID
Q9R1C8
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  4
1
Ki = 0.32 nM
   TI
   LI
   LO
   TS
2
Ki = 0.75 nM
   TI
   LI
   LO
   TS
3
Ki = 54 nM
   TI
   LI
   LO
   TS
4
Ki = 114 nM
   TI
   LI
   LO
   TS