Brief Information of the Compound and Protein
Compound Name
4-(4-Methylpiperazin-1-yl)-2-(2-naphthylmethyl)-1H-benzimidazole
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PubChem ID
CID: 45488166
SID: 96101413
Canonical SMILES
C(c1nc2c(cccc2[nH]1)N1CCNCC1)c1ccc2ccccc2c1
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Compound Formula C22H22N4
Compound Structure
Protein Name
5-hydroxytryptamine receptor 6
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Small molecule receptor (family A GPCR)
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Monoamine receptor
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Serotonin receptor
Uniprot ID
P50406
Gene Name
HTR6
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
Ki = 17 nM
   TI
   LI
   LO
   TS
CL000006 HEK293 Homo sapiens (Human)  1
1
Ki = 49 nM
   TI
   LI
   LO
   TS