Brief Information of the Compound and Protein
Compound Name
4-methoxy-2-(2-methoxy-4,6-dimethylphenyl)-6-methyl-5-(pentan-3-yloxy)pyrimidine
    Show/Hide
PubChem ID
CID: 44587456
Canonical SMILES
CCC(CC)Oc1c(C)nc(nc1OC)-c1c(C)cc(C)cc1OC
    Show/Hide
Compound Formula C20H28N2O3
Compound Structure
Protein Name
Corticotropin-releasing factor receptor 1
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Corticotropin releasing factor receptor
>
Corticotropin releasing factor receptor
Uniprot ID
P34998
Gene Name
CRHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000367 AtT-20 Mus musculus (Mouse)  1
1
IC50 = 19 nM
   TI
   LI
   LO
   TS
CL000016 IMR-32 Homo sapiens (Human)  1
1
Ki = 8 nM
   TI
   LI
   LO
   TS