Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1S,2R,10R,11S,14S,15S)-14-hydroxy-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
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 PubChem ID
CID: 6013
SID: 14873306
Canonical SMILES
C[C@]12CC[C@H]3[C@@H](CCC4=CC(=O)CC[C@]34C)[C@@H]1CC[C@@H]2O
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Compound Formula C19H28O2
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  3
1
IC50 = 4.17 nM
   TI
   LI
   LO
   TS
2
IC50 = 4.27 nM
   TI
   LI
   LO
   TS
3
IC50 = 4.571 nM
   TI
   LI
   LO
   TS
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 1.1 nM
   TI
   LI
   LO
   TS
CL000257 MDA-kb2
 Cell Line Info 
Homo sapiens (Human)  1
1
EC50 = 3.162 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 EC50 = 1.9 nM
2 IC50 = 2.7 nM
3 IC50 = 30 nM
4 Kd = 0.4 nM
5 Ki = 29 nM