Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(1S)-1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-2-benzofuran-5-carbonitrile
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 PubChem ID
CID: 146570
SID: 14826334
Canonical SMILES
CN(C)CCC[C@]1(OCc2cc(ccc12)C#N)c1ccc(F)cc1
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Compound Formula C20H21FN2O
Compound Structure
Protein Name
 Protein Info 
Sodium-dependent serotonin transporter
Protein Classification
Transporter
>
Electrochemical transporter
>
SLC superfamily of solute carriers
>
SLC06 neurotransmitter transporter family
Uniprot ID
P31645
Gene Name
SLC6A4
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 2.1 nM
   TI
   LI
   LO
   TS
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  3
1
IC50 = 4600 nM
   TI
   LI
   LO
   TS
2
Kd = 2.6 nM
   TI
   LI
   LO
   TS
3
Ki = 7.4 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  1
1
Ki = 1 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 1 nM