Brief Information of the Compound and Protein
Compound Name
(2R)-3-[[2-[[(1S)-1-(4-Fluorophenyl)ethyl]amino]-6-[(5-methyl-1H-pyrazol-3-yl)amino]pyrimidin-4-yl]amino]propane-1,2-diol
    Show/Hide
PubChem ID
CID: 24949705
SID: 56247479
Canonical SMILES
Cc1cc(Nc2cc(NC[C@@H](O)CO)nc(N[C@@H](C)c3ccc(F)cc3)n2)n[nH]1
    Show/Hide
Compound Formula C19H24FN7O2
Compound Structure
Protein Name
High affinity nerve growth factor receptor
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase Trk family
Uniprot ID
P04629
Gene Name
NTRK1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000243 MCF-10A Homo sapiens (Human)  1
1
EC50 = 60 nM
   TI
   LI
   LO
   TS