Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4,4-Spiropentyl-2-(4-chlorophenyl)isoquinoline-1,3(2H,4H)-dione
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 PubChem ID
CID: 44568084
Canonical SMILES
Clc1ccc(cc1)N1C(=O)c2ccccc2C2(CCCC2)C1=O
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Compound Formula C19H16ClNO2
Compound Structure
Protein Name
 Protein Info 
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
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Nuclear hormone receptor subfamily 3
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Nuclear hormone receptor subfamily 3 group C
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Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 2100 nM
   TI
   LI
   LO
   TS
CL000078 T-47D
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 1300 nM
   TI
   LI
   LO
   TS