Brief Information of the Compound and Protein
Compound Name
N-[(3R)-1-[(6-fluoronaphthalen-2-yl)methyl]pyrrolidin-3-yl]-2-[1-(2-hydroxybenzoyl)piperidin-4-ylidene]acetamide
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PubChem ID
CID: 44512617
SID: 85847193
Canonical SMILES
Oc1ccccc1C(=O)N1CCC(CC1)=CC(=O)N[C@@H]1CCN(Cc2ccc3cc(F)ccc3c2)C1
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Compound Formula C29H30FN3O3
Compound Structure
Protein Name
C-C chemokine receptor type 3
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51677
Gene Name
CCR3
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000795 300-19 Mus musculus (Mouse)  2
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
2
IC50 = 8.4 nM
   TI
   LI
   LO
   TS