Brief Information of the Compound and Protein
Compound Name
2-((4-(2-Fluorophenyl)piperidin-1-yl)methyl)-1-methyl-1H-benzo-[d]imidazole
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PubChem ID
CID: 24815439
SID: 49814623
Canonical SMILES
Cn1c(CN2CCC(CC2)c2ccccc2F)nc2ccccc12
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Compound Formula C20H22FN3
Compound Structure
Protein Name
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
Q14416
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000064 Chem-1 Rattus norvegicus (Rat)  1
1
EC50 = 130 nM
   TI
   LI
   LO
   TS
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
EC50 = 125.89 nM
   TI
   LI
   LO
   TS
2
EC50 = 3981.07 nM
   TI
   LI
   LO
   TS