Brief Information of the Compound and Protein
Compound Name
2-(3,4-difluorophenyl)-N-ethyl-N-(3-(6-fluoro-3H-spiro[isobenzofuran-1,4'-piperidine]-1'-yl)propyl)-2-(2-oxopyrrolidin-1-yl)acetamide
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PubChem ID
CID: 10459635
SID: 15481492
Canonical SMILES
CCN(CCCN1CCC2(CC1)OCc1ccc(F)cc21)C(=O)C(N1CCCC1=O)c1ccc(F)c(F)c1
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Compound Formula C29H34F3N3O3
Compound Structure
Protein Name
Melanin-concentrating hormone receptor 1
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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MCH receptor
Uniprot ID
Q99705
Gene Name
MCHR1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  1
1
IC50 = 0.71 nM
   TI
   LI
   LO
   TS