Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(3-chloro-5-(4-(2-fluoro-3-(trifluoromethyl)phenyl)thiazol-2-ylcarbamoyl)pyridin-2-yl)piperazine-2-carboxylic acid
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 PubChem ID
CID: 15949825
SID: 22421242
Canonical SMILES
OC(=O)C1CN(CCN1)c1ncc(cc1Cl)C(=O)Nc1nc(cs1)-c1cccc(c1F)C(F)(F)F
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Compound Formula C21H16ClF4N5O3S
Compound Structure
Protein Name
 Protein Info 
Thrombopoietin receptor
Protein Classification
Membrane receptor
Uniprot ID
P40238
Gene Name
MPL
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000077 Ba/F3
 Cell Line Info 
Mus musculus (Mouse)  1
1
EC50 = 129 nM
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