Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(1,1,4,4-tetramethyl-1,2,3,4-tetrahydronaphthalene-7-carboxamido)benzoic acid
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 PubChem ID
CID: 2126
SID: 14925445
Canonical SMILES
CC1(C)CCC(C)(C)c2cc(ccc12)C(=O)Nc1ccc(cc1)C(O)=O
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Compound Formula C22H25NO3
Compound Structure
Protein Name
 Protein Info 
Retinoic acid receptor beta
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 1
>
Nuclear hormone receptor subfamily 1 group B
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Nuclear hormone receptor subfamily 1 group B member 2
Uniprot ID
P10826
Gene Name
RARB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
EC50 = 8.6 nM
   TI
   LI
   LO
   TS
CL000035 NIH 3T3
 Cell Line Info 
Mus musculus (Mouse)  2
1
EC50 = 19.95 nM
   TI
   LI
   LO
   TS
2
EC50 = 50.12 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Kd = 1361 nM
2 Kd = 1400 nM