Brief Information of the Compound and Protein
Compound Name
(3Z)-3-[(3,5-dimethyl-1H-pyrrol-2-yl)methylidene]-2,3-dihydro-1H-indol-2-one
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PubChem ID
CID: 5329098
SID: 14847387
Canonical SMILES
Cc1cc(C)c(\C=C2/C(=O)Nc3ccccc23)[nH]1
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Compound Formula C15H14N2O
Compound Structure
Protein Name
Platelet-derived growth factor receptor beta
Protein Classification
Enzyme
>
Kinase
>
Protein Kinase
>
TK protein kinase group
>
Tyrosine protein kinase PDGFR family
Uniprot ID
P09619
Gene Name
PDGFRB
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000117 SF539 Homo sapiens (Human)  1
1
IC50 = 2400 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 68 nM
2 IC50 = 400 nM
3 IC50 = 680 nM
4 IC50 = 10100 nM
5 IC50 = 10500 nM
6 IC50 = 20260 nM
7 IC50 = 22900 nM