Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R)-1-[(2-Chloro-4-pyrrolidin-1-ylphenyl)sulfonyl]-4-[4-fluoro-2-(trifluoromethyl)phenyl]-2-methylpiperazine
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 PubChem ID
CID: 44248208
SID: 85281904
Canonical SMILES
C[C@@H]1CN(CCN1S(=O)(=O)c1ccc(cc1Cl)N1CCCC1)c1ccc(F)cc1C(F)(F)F
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Compound Formula C22H24ClF4N3O2S
Compound Structure
Protein Name
 Protein Info 
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
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Oxidoreductase
Uniprot ID
P50172
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  2
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
2
IC50 = 12 nM
   TI
   LI
   LO
   TS