Brief Information of the Compound and Protein
Compound Name
(2R)-4-(4-(4-Fluoro-2-(trifluoromethyl)phenyl)-2-methylpiperazin-1-ylsulfonyl)benzamide
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PubChem ID
CID: 44248095
SID: 85281787
Canonical SMILES
C[C@@H]1CN(CCN1S(=O)(=O)c1ccc(cc1)C(N)=O)c1ccc(F)cc1C(F)(F)F
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Compound Formula C19H19F4N3O3S
Compound Structure
Protein Name
11-beta-hydroxysteroid dehydrogenase 1
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P50172
Gene Name
HSD11B1
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 10 nM
   TI
   LI
   LO
   TS
2
IC50 = 25 nM
   TI
   LI
   LO
   TS