Brief Information of the Compound and Protein
Compound Name
 Compound Info 
(2R,3S)-3-({[3-(1,1-Dioxidotetrahydro-2H-1,2-thiazin-2-yl)-5-(ethylamino)phenyl]carbonyl}amino)-2-hydroxy-4-phenyl-N-(phenylmethyl)-1-butanaminium formate
    Show/Hide
 PubChem ID
CID: 24878892
SID: 50134321
Canonical SMILES
CCNc1cc(C(=O)N[C@@H](Cc2ccccc2)[C@H](O)CNCc2ccccc2)cc(N2CCCCS2(=O)=O)c1.O=CO
    Show/Hide
Compound Formula C31H40N4O6S
Compound Structure
Protein Name
 Protein Info 
Beta-secretase 2
Protein Classification
Enzyme
>
Protease
>
Aspartic protease
>
Aspartic protease AA clan
>
Aspartic protease A1A subfamily
Uniprot ID
Q9Y5Z0
Gene Name
BACE2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 32360 nM
   TI
   LI
   LO
   TS