Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-benzyl-1-(2,6-difluoro-benzyl)-3-{2-[methyl-(2-pyridin-2-yl-ethyl)-amino]-ethyl}-5,6,7,8-tetrahydro-1H-pyrido[4,3-d]pyrimidine-2,4-dione
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 PubChem ID
CID: 44435825
Canonical SMILES
CN(CCc1ccccn1)CCn1c(=O)c2CN(Cc3ccccc3)CCc2n(Cc2c(F)cccc2F)c1=O
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Compound Formula C31H33F2N5O2
Compound Structure
Protein Name
 Protein Info 
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GnRH receptor
Uniprot ID
P30968
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
Ki = 990 nM
   TI
   LI
   LO
   TS