Brief Information of the Compound and Protein
Compound Name
 Compound Info 
1-(2,6-difluoro-benzyl)-3-(3-methoxy-phenyl)-5,6,7,8-tetrahydro-1H-pyrido[3,4-d]pyrimidine-2,4-dione
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 PubChem ID
CID: 44435818
Canonical SMILES
COc1cccc(c1)-n1c(=O)c2CCNCc2n(Cc2c(F)cccc2F)c1=O
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Compound Formula C21H19F2N3O3
Compound Structure
Protein Name
 Protein Info 
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
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Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GnRH receptor
Uniprot ID
P30968
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
Ki = 970 nM
   TI
   LI
   LO
   TS