Brief Information of the Compound and Protein
Compound Name
6-(2,4-dimethylbenzyl)-1-(2,6-difluorobenzyl)-3-((1-methylpiperidin-3-yl)methyl)-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidine-2,4(1H,3H)-dione
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PubChem ID
CID: 44436006
Canonical SMILES
CN1CCCC(Cn2c(=O)c3CN(Cc4ccc(C)cc4C)CCc3n(Cc3c(F)cccc3F)c2=O)C1
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Compound Formula C30H36F2N4O2
Compound Structure
Protein Name
Gonadotropin-releasing hormone receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Short peptide receptor (family A GPCR)
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GnRH receptor
Uniprot ID
P30968
Gene Name
GNRHR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000053 COS-7 Chlorocebus aethiops (Green monkey)  1
1
Ki > 10000 nM
   TI
   LI
   LO
   TS