Brief Information of the Compound and Protein
Compound Name
(2S)-N-[3,5-bis(trifluoromethyl)benzyl]-2-cyclopropyl-4-[(1R,3R')-3'methyl-1'H-spiro[indene-1,4'-piperidin]-1'yl]butanamide
    Show/Hide
PubChem ID
CID: 44415880
Canonical SMILES
C[C@H]1CN(CC[C@@H](C2CC2)C(=O)NCc2cc(cc(c2)C(F)(F)F)C(F)(F)F)CC[C@@]11C=Cc2ccccc12
    Show/Hide
Compound Formula C30H32F6N2O
Compound Structure
Protein Name
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
IC50 = 14 nM
   TI
   LI
   LO
   TS