Brief Information of the Compound and Protein
Compound Name
2-(3-((1-(3-(2-chlorophenoxy)benzyl)piperidin-4-yl)carbamoyl)-3-phenylpyrrolidin-1-yl)-2-methylpropanoic acid
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PubChem ID
CID: 11541506
SID: 16643566
Canonical SMILES
CC(C)(N1CCC(C1)(C(=O)NC1CCN(Cc2cccc(Oc3ccccc3Cl)c2)CC1)c1ccccc1)C(O)=O
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Compound Formula C33H38ClN3O4
Compound Structure
Protein Name
C-C chemokine receptor type 8
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
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Peptide receptor (family A GPCR)
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Chemokine receptor
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CC chemokine receptor
Uniprot ID
P51685
Gene Name
CCR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000233 L1.2 Mus musculus (Mouse)  2
1
IC50 = 1 nM
   TI
   LI
   LO
   TS
2
Ki = 6 nM
   TI
   LI
   LO
   TS