Brief Information of the Compound and Protein
Compound Name
2-(4-{1-[3-(2-chloro-phenoxy)-benzyl]-piperidin-4-ylcarbamoyl}-4-phenyl-piperidin-1-yl)-2-methyl-propionic acid
    Show/Hide
PubChem ID
CID: 11685733
SID: 16789885
Canonical SMILES
CC(C)(N1CCC(CC1)(C(=O)NC1CCN(Cc2cccc(Oc3ccccc3Cl)c2)CC1)c1ccccc1)C(O)=O
    Show/Hide
Compound Formula C34H40ClN3O4
Compound Structure
Protein Name
C-C chemokine receptor type 8
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P51685
Gene Name
CCR8
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000233 L1.2 Mus musculus (Mouse)  2
1
IC50 = 4 nM
   TI
   LI
   LO
   TS
2
Ki = 9 nM
   TI
   LI
   LO
   TS