Brief Information of the Compound and Protein
Compound Name
(2E,4E)-6-((6-tert-butyl-1,1-dimethyl-2,3-dihydro-1H-inden-4-yl)(isopropyl)amino)-3-methylhexa-2,4-dienoic acid
    Show/Hide
PubChem ID
CID: 44410568
Canonical SMILES
CC(C)N(C\C=C\C(\C)=C\C(O)=O)c1cc(cc2c1CCC2(C)C)C(C)(C)C
    Show/Hide
Compound Formula C25H37NO2
Compound Structure
Protein Name
Retinoic acid receptor RXR-gamma
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 2
>
Nuclear hormone receptor subfamily 2 group B
>
Nuclear hormone receptor subfamily 2 group B member 3
Uniprot ID
P48443
Gene Name
RXRG
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1 Chlorocebus aethiops (Green monkey)  1
1
EC50 = 262 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 121 nM