Brief Information of the Compound and Protein
Compound Name
 Compound Info 
3-p-Tolyl-8,9-dihydro-7H-benzocycloheptene-6-carboxylic acid (4-{[methyl-(tetrahydro-pyran-4-yl)-amino]-methyl}-phenyl)-amide
    Show/Hide
 PubChem ID
CID: 3013430
SID: 15529916
Canonical SMILES
Cc1ccc(-c2ccc3c(c2)C=C(C(=O)Nc2ccc(CN(C)C4CCOCC4)cc2)CCC3)cc1
    Show/Hide
Compound Formula C32H36N2O2
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 28.84 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  11
1
Ki = 23.99 nM
   TI
   LI
   LO
   TS
2
Ki = 69.18 nM
   TI
   LI
   LO
   TS
3
Ki = 104.71 nM
   TI
   LI
   LO
   TS
4
Ki = 151.36 nM
   TI
   LI
   LO
   TS
5
Ki = 229.09 nM
   TI
   LI
   LO
   TS
6
Ki = 302 nM
   TI
   LI
   LO
   TS
7
Ki = 588.84 nM
   TI
   LI
   LO
   TS
8
Ki = 758.58 nM
   TI
   LI
   LO
   TS
9
Ki = 2041.74 nM
   TI
   LI
   LO
   TS
10
Ki = 2570.4 nM
   TI
   LI
   LO
   TS
11
Ki = 4786.3 nM
   TI
   LI
   LO
   TS