Brief Information of the Compound and Protein
Compound Name
 Compound Info 
6-methyl-1'-[2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethyl]spiro[1,4-dihydro-2H-benzo[d][1,3]oxazine-4,4'-(hexahydropyridine)]-2-one
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 PubChem ID
CID: 9953769
SID: 14929247
Canonical SMILES
Cc1oc(nc1CCN1CCC2(CC1)OC(=O)Nc1ccc(C)cc21)-c1ccccc1
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Compound Formula C25H27N3O3
Compound Structure
Protein Name
 Protein Info 
C-C chemokine receptor type 2
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Peptide receptor (family A GPCR)
>
Chemokine receptor
>
CC chemokine receptor
Uniprot ID
P41597
Gene Name
CCR2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
Ki = 208.93 nM
   TI
   LI
   LO
   TS
CL000006 HEK293
 Cell Line Info 
Homo sapiens (Human)  8
1
Ki = 58.88 nM
   TI
   LI
   LO
   TS
2
Ki = 173.78 nM
   TI
   LI
   LO
   TS
3
Ki = 218.78 nM
   TI
   LI
   LO
   TS
4
Ki = 446.68 nM
   TI
   LI
   LO
   TS
5
Ki = 524.81 nM
   TI
   LI
   LO
   TS
6
Ki = 851.14 nM
   TI
   LI
   LO
   TS
7
Ki = 2511.89 nM
   TI
   LI
   LO
   TS
8
Ki = 6309.57 nM
   TI
   LI
   LO
   TS