Brief Information of the Compound and Protein
Compound Name
 Compound Info 
4-(4-methanesulfonylphenyl)-3-phenyl-2,5-dihydrofuran-2-one
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 PubChem ID
CID: 5090
SID: 14752370
Canonical SMILES
CS(=O)(=O)c1ccc(cc1)C1=C(C(=O)OC1)c1ccccc1
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Compound Formula C17H14O4S
Compound Structure
Protein Name
 Protein Info 
Prostaglandin G/H synthase 2
Protein Classification
Enzyme
>
Oxidoreductase
Uniprot ID
P35354
Gene Name
PTGS2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000763 143.98.2
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 12 nM
   TI
   LI
   LO
   TS
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 20 nM
   TI
   LI
   LO
   TS
CL000880 COS
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 32 nM
   TI
   LI
   LO
   TS
CL000012 Sf21
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  3
1
IC50 = 120 nM
   TI
   LI
   LO
   TS
2
IC50 = 170 nM
   TI
   LI
   LO
   TS
3
IC50 = 679 nM
   TI
   LI
   LO
   TS
CL000013 Sf9
 Cell Line Info 
Spodoptera frugiperda (Fall armyworm)  1
1
IC50 = 107 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 IC50 = 15 nM
2 IC50 = 25 nM
3 IC50 = 292 nM
4 IC50 = 300 nM
5 IC50 = 329 nM
6 IC50 = 340 nM
7 IC50 = 360 nM
8 IC50 = 427.9 nM
9 IC50 = 480 nM
10 IC50 = 500 nM
11 IC50 = 530 nM
12 IC50 = 760 nM
13 IC50 = 1000 nM
14 IC50 = 1500 nM
15 IC50 = 2000 nM