Brief Information of the Compound and Protein
Compound Name
 Compound Info 
ONAPRISTONE
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 PubChem ID
CID: 5311505
SID: 12013541
Canonical SMILES
CN(C)c1ccc(cc1)[C@H]1C[C@]2(C)[C@@H](CC[C@]2(O)CCCO)[C@@H]2CCC3=CC(=O)CCC3=C12
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Compound Formula C29H39NO3
Compound Structure
Protein Name
 Protein Info 
Progesterone receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 3
Uniprot ID
P06401
Gene Name
PGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  3
1
EC50 = 2.2 nM
   TI
   LI
   LO
   TS
2
IC50 = 1.6 nM
   TI
   LI
   LO
   TS
3
IC50 = 2.2 nM
   TI
   LI
   LO
   TS
CL000078 T-47D
 Cell Line Info 
Homo sapiens (Human)  1
1
IC50 = 3.3 nM
   TI
   LI
   LO
   TS
Biochemical Assays
1 Ki = 18 nM