Brief Information of the Compound and Protein
Compound Name
 Compound Info 
8,8-dimethyl-4-(trifluoromethyl)-1H,2H,8H,9H-pyrido[3,2-g]quinolin-2-one
    Show/Hide
 PubChem ID
CID: 10851308
SID: 15893612
Canonical SMILES
CC1(C)Nc2cc3[nH]c(=O)cc(c3cc2C=C1)C(F)(F)F
    Show/Hide
Compound Formula C15H13F3N2O
Compound Structure
Protein Name
 Protein Info 
Androgen receptor
Protein Classification
Transcription factor
>
Nuclear receptor
>
Nuclear hormone receptor subfamily 3
>
Nuclear hormone receptor subfamily 3 group C
>
Nuclear hormone receptor subfamily 3 group C member 4
Uniprot ID
P10275
Gene Name
AR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
Ki = 86 nM
   TI
   LI
   LO
   TS
CL000044 CV-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  3
1
IC50 = 27 nM
   TI
   LI
   LO
   TS
2
IC50 = 58 nM
   TI
   LI
   LO
   TS
3
Ki = 73 nM
   TI
   LI
   LO
   TS