Brief Information of the Compound and Protein
Compound Name
4-[3-(4-Bromo-phenyl)-8-tert-butyl-2-oxo-1,3-diaza-spiro[4.5]dec-1-ylmethyl]-N-(2H-tetrazol-5-yl)-benzamide
    Show/Hide
PubChem ID
CID: 11757662
SID: 16865438
Canonical SMILES
CC(C)(C)C1CCC2(CN(C(=O)N2Cc2ccc(cc2)C(=O)Nc2nnn[nH]2)c2ccc(Br)cc2)CC1
    Show/Hide
Compound Formula C27H32BrN7O2
Compound Structure
Protein Name
Glucagon receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Glucagon-like receptor
>
Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 156 nM
   TI
   LI
   LO
   TS
2
IC50 = 655 nM
   TI
   LI
   LO
   TS