Brief Information of the Compound and Protein
Compound Name
4-{3-[1-(4-Bromo-phenyl)-ethyl]-8-tert-butyl-2-oxo-1,3-diaza-spiro[4.5]dec-1-ylmethyl}-N-(2H-tetrazol-5-yl)-benzamide
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PubChem ID
CID: 10416067
SID: 15433754
Canonical SMILES
CC(N1CC2(CCC(CC2)C(C)(C)C)N(Cc2ccc(cc2)C(=O)Nc2nnn[nH]2)C1=O)c1ccc(Br)cc1
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Compound Formula C29H36BrN7O2
Compound Structure
Protein Name
Glucagon receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
>
Peptide receptor (family B GPCR)
>
Glucagon-like receptor
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Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 30 nM
   TI
   LI
   LO
   TS
2
IC50 = 164 nM
   TI
   LI
   LO
   TS