Brief Information of the Compound and Protein
Compound Name
3-{4-[8-tert-Butyl-3-(3-chloro-phenyl)-2-oxo-1,3-diaza-spiro[4.5]dec-1-ylmethyl]-benzoylamino}-propionic acid
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PubChem ID
CID: 10369580
SID: 15383122
Canonical SMILES
CC(C)(C)C1CCC2(CN(C(=O)N2Cc2ccc(cc2)C(=O)NCCC(O)=O)c2cccc(Cl)c2)CC1
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Compound Formula C29H36ClN3O4
Compound Structure
Protein Name
Glucagon receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Glucagon-like receptor
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Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 351 nM
   TI
   LI
   LO
   TS
2
IC50 = 601 nM
   TI
   LI
   LO
   TS