Brief Information of the Compound and Protein
Compound Name
 Compound Info 
2-N-[[4-[[[4-bromo-2-(trifluoromethoxy)phenyl]methylamino]methyl]cyclohexyl]methyl]-4-N,4-N-dimethylquinazoline-2,4-diamine
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 PubChem ID
CID: 44390385
Canonical SMILES
CN(C)c1nc(NCC2CCC(CNCc3ccc(Br)cc3OC(F)(F)F)CC2)nc2ccccc12
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Compound Formula C26H31BrF3N5O
Compound Structure
Protein Name
 Protein Info 
Alpha-2A adrenergic receptor
Protein Classification
Membrane receptor
>
Family A G protein-coupled receptor
>
Small molecule receptor (family A GPCR)
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Monoamine receptor
>
Adrenergic receptor
Uniprot ID
P08913
Gene Name
ADRA2A
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000109 COS-1
 Cell Line Info 
Chlorocebus aethiops (Green monkey)  1
1
IC50 = 31 nM
   TI
   LI
   LO
   TS