Brief Information of the Compound and Protein
Compound Name
 Compound Info 
7-(dimethylamino)-8-(2-phenylethynyl)-4-[3-(triazol-1-yl)phenyl]-1,3-dihydro-1,5-benzodiazepin-2-one
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 PubChem ID
CID: 10204007
SID: 15202129
Canonical SMILES
CN(C)c1cc2N=C(CC(=O)Nc2cc1C#Cc1ccccc1)c1cccc(c1)-n1ccnn1
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Compound Formula C27H22N6O
Compound Structure
Protein Name
 Protein Info 
Metabotropic glutamate receptor 2
Protein Classification
Membrane receptor
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Family C G protein-coupled receptor
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Small molecule receptor (family C GPCR)
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Neurotransmitter receptor (family C GPCR)
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Metabotropic glutamate receptor
Uniprot ID
P31421
Gene Name
GRM2
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO
 Cell Line Info 
Cricetulus griseus (Chinese hamster)  1
1
IC50 = 36 nM
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