Brief Information of the Compound and Protein
Compound Name
4-Cyano-5-(2-ethyl-butyrylamino)-3-methyl-thiophene-2-carboxylic acid (2,4-dichloro-benzyl)-isopropyl-amide
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PubChem ID
CID: 10435275
SID: 15455058
Canonical SMILES
CCC(CC)C(=O)Nc1sc(C(=O)N(Cc2ccc(Cl)cc2Cl)C(C)C)c(C)c1C#N
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Compound Formula C23H27Cl2N3O2S
Compound Structure
Protein Name
Glucagon receptor
Protein Classification
Membrane receptor
>
Family B G protein-coupled receptor
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Peptide receptor (family B GPCR)
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Glucagon-like receptor
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Glucagon receptor
Uniprot ID
P47871
Gene Name
GCGR
Table of Molecular Bioactivities Related to the Compound and Protein
Cell-based Assay
Cell Line ID Cell Line Name Cell Line Organism
CL000011 CHO Cricetulus griseus (Chinese hamster)  2
1
IC50 = 41 nM
   TI
   LI
   LO
   TS
2
IC50 = 153 nM
   TI
   LI
   LO
   TS